抗體(antibody)毒素(drug)連接物(linker)構建ADC-抗體藥物偶連物

ADCs的組成包括**抗原特異性mAb，穩(wěn)定的可裂解或不可裂解的linker，以及有效的細胞毒性載荷。 rug)、連接物(linker)構建ADC-抗體藥物偶連物

ADCs的組成包括**抗原特異性mAb，穩(wěn)定的可裂解或不可裂解的linker，以及有效的細胞毒性載荷。

ADC由以下三部分組成：

抗體（antibody）：其作用是特異性識別靶細胞

毒素（drug）：起到損傷細胞的作用

連接物（linker）：連接抗體與毒素

相關資料：

DBCO-PEG4-vc-PAB-MMAE

DBCO-PEG4-MMAF

DBCO-PEG4-Ahx-DM1

DBCO-PEG4-vc-PAB-Duocarmycin SA

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin SA

DBCO-PEG4-VA-PBD

DBCO-PEG4-vc-PAB-MMAF

DBCO-PEG4-vc-PAB-MMAD

DBCO-PEG4-vc-PAB-Duocarmycin TM

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin TM

DBCO-PEG4-vc-PAB-Duocarmycin DM

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM

DBCO-PEG4-VC-PAB-DMAE-PNU159682

DBCO-PEG4-DMAE-PNU159682

DBCO-PEG4-GGFG-DX8951

DBCO-PEG4-vc-PAB-Ahx-DM1

DBCO-PEG8-VA-PAB-SG3199

Gly3-vc-PAB-MMAE

Gly3-MMAF

Gly5-Ahx-DM1

PNU159682-EDA-Gly3

ADC pre-screening kit A

Protein A-DM1

Protein A-MMAE

Protein A-MMAF

Protein A-Duocarmycin

Protein A-Calicheamicin

Protein A-PBD

ADC pre-screening kit G

Protein G-DM1

Protein G-MMAE

Protein G-MMAF

Protein G-Duocarmycin

Protein G-Amanitin

Protein G-Amanitin

Rabbit Anti-vc-PAB-MMAE pAb

Mouse Anti-vc-PAB-MMAE mAb (B11F11)

Rabbit Anti-MMAF pAb

Mouse Anti-MMAF mAb (F3B11)

Mouse Anti-MMAE / F mAb (B12A2)

Mouse Anti-MMAE /F mAb (C12A1)

Rabbit Anti-DM1/4 pAb

Mouse Anti-DM1/4 mAb (F1D5)

Mouse Anti-DM1/4 mAb (G2F3)

Rabbit Anti-Calicheamicin pAb

Mouse Anti-Calicheamicin mAb (B1G9)

Mouse Anti-Calicheamicin mAb (C1F12)

Rabbit Anti-Duocarmycin pAb 

Mouse Anti-Duocarmycin mAb (E11A1)

Mouse Anti-Duocarmycin mAb (H7A9)

Mouse Anti-Duocarmycin mAb (E6B3) 

Rabbit Anti-PNU-159682 pAb

Mouse Anti-PNU-159682 mAb (F7F2)

Mouse Anti-PNU-159682 mAb (C1E3)

Mouse Anti-PNU-159682 mAb (D12H11)

Rabbit Anti-Amanitin pAb

Mouse Anti-Amanitin mAb (H3E1)

Mouse Anti-Amanitin mAb (H12D6)

Mouse Anti-Amanitin mAb (C2C4)

Rabbit Anti-SN38 pAb

Mouse Anti-SN38 mAb (10F11A9D6)

Mouse Anti-SN38 mAb (8E10F12F3)

Mouse Anti-SN38 mAb (8E10A4A1)

Rabbit Anti-PBD SG3199 pAb

Mouse Anti-PBD SG3199 (7H6H9A6) mAb

Mouse Anti-PBD SG3199 (8G2H12A9) mAb

Mouse Anti-PBD SG3199 (8B3D12G1) mAb