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美國CIL一級(jí)代理商/經(jīng)銷商(穩(wěn)定同位素標(biāo)準(zhǔn)品)
西安瑞禧生物科技有限公司是國內(nèi)CIL同位素標(biāo)準(zhǔn)品標(biāo)記公司的總代理商,我公司代理的美國CIL公司的產(chǎn)品 貨期快 價(jià)格低,西安瑞禧生物科技有限公司是美國CIL的一級(jí)代理商和經(jīng)銷商。
我公司可以提供各種同位素標(biāo)記的多肽 抗體 蛋白 藥物 或其他小分子產(chǎn)品。
CIL(穩(wěn)定同位素標(biāo)準(zhǔn)品、環(huán)境分析標(biāo)準(zhǔn)品)
CIL是世界上第一個(gè)生產(chǎn)穩(wěn)定同位素標(biāo)記化合物的生廠商,主要標(biāo)記同位素有13C、D、15N、18O和17O,目前擁有8000多種標(biāo)記化合物。
穩(wěn)定同位素在分析中應(yīng)用于光譜分析,核磁共振分析,密度分析,氣相色譜分析,質(zhì)譜分析,中子活化分析,紅外光譜分析,氣相色譜-質(zhì)譜分析,稀釋分析等。
穩(wěn)定性同位素及其化合物之間的化學(xué)性質(zhì)和生物性質(zhì)是相同的,只是具有不同的核物理性質(zhì)。因此,可以用穩(wěn)定性同位素作為示蹤原子,制成含有穩(wěn)定性同位素的標(biāo)記化合物,利用其與相應(yīng)非標(biāo)記元素的不同特性,通過質(zhì)譜儀、核磁共振儀等分析儀器來測定穩(wěn)定同位素反應(yīng)后的位置、數(shù)量及其轉(zhuǎn)變量等,從而了解反應(yīng)的機(jī)理、途徑、效果等。
元素的同位素組成常用同位素豐度表示,同位素豐度是指一種元素的同位素混合物中,某特定同位素的原子數(shù)與該元素的總原子數(shù)之比。
產(chǎn)品種類包括:
用于科研:氨基酸、膽汁酸、生物標(biāo)準(zhǔn)品、緩沖試劑、細(xì)胞生長培養(yǎng)基、細(xì)胞代謝和代謝組學(xué)、化學(xué)標(biāo)記試劑、脂肪酸類和脂類、代謝產(chǎn)物和底物、甲基標(biāo)記試劑盒和氨基酸、核酸、蛋白質(zhì)標(biāo)準(zhǔn)品、蛋白試劑、15N標(biāo)記的鹽、類固醇和激素、合成中間體、維生素等。
用于環(huán)境污染物分析:農(nóng)藥和農(nóng)藥代謝產(chǎn)物標(biāo)準(zhǔn)品、全氟化合物標(biāo)準(zhǔn)品、二惡英和呋喃標(biāo)準(zhǔn)、二惡英和呋喃方法標(biāo)準(zhǔn),標(biāo)準(zhǔn)混合物和參考材料、PCB標(biāo)準(zhǔn)和標(biāo)準(zhǔn)混合物、溴化阻燃劑、二惡英/呋喃Plus PCB標(biāo)準(zhǔn)混合物、多環(huán)芳烴(PAH)標(biāo)準(zhǔn)品和標(biāo)準(zhǔn)混合物、優(yōu)先污染物標(biāo)準(zhǔn)混合物、優(yōu)先污染物,內(nèi)分泌干擾物和化學(xué)污染物標(biāo)準(zhǔn)、農(nóng)藥和農(nóng)藥代謝標(biāo)準(zhǔn)品、PPCP、鄰苯二甲酸酯和鄰苯二甲酸酯代謝物標(biāo)準(zhǔn)品、全氟化合物標(biāo)準(zhǔn)品。
美國劍橋同位素CIL是世界上第一個(gè)生產(chǎn)穩(wěn)定性同位素標(biāo)記化合物的生產(chǎn)商,以其領(lǐng)先的技術(shù)雄踞同位素分離領(lǐng)域。20年來,CIL一直研究穩(wěn)定性同位素與穩(wěn)定性同位素標(biāo)記化合物的開發(fā),生產(chǎn)。主要標(biāo)記性同位素有13C、12C、D、15N、18O和17O,目前已經(jīng)擁有8000多種標(biāo)記化合物。CIL的產(chǎn)品均能應(yīng)用于不同的領(lǐng)域,如物理,化學(xué),生物醫(yī)學(xué),分析,診斷研究以及環(huán)境測試。
Cambridge Isotope Laboratories, Inc. (CIL) is the world’sleading producer of stable isotopes and stable isotope-labeled compounds. Withover 400 employees and laboratories in four countries, CIL specializes in theprocess of labeling biochemical and organic compounds with highly enriched,stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen. Ourchemists substitute common atoms (e.g., 1H, 12C, 14N, 16O) withrare, highly valued isotopes (e.g., 2H or D, 13C, 15N,18O) so thatthe final product can be readily measured or traced using mass spectrometry(MS) or nuclear magnetic resonance (NMR). CIL’s products are utilized inlaboratories, medical, government and academic research centers and health carefacilities worldwide. We are proud that CIL products have contributed tomedical advancements in cancer research, new-drug development, environmentalanalysis, genomics and proteomics, and medical diagnostic research. In the pastdecade, as the fields of proteomics and metabolomics have developed as leadingtechniques for determining biomarkers for disease presence, progression and themonitoring of therapeutic response, CIL has worked closely with industryleaders and researchers to provide the stable isotope-labeled tools needed forimproved quantitation of complex systems.
CIL's vision began whenit was founded in 1981 by Dr. Joel Bradley, an organic chemist from MIT.Drawing on a commitment to high-quality products, superior customer service,innovative new products and breadth of product lines, CIL quickly emerged as aleader in its field. CIL now produces more than 15,000 products and has ISO13485, ISO/IEC 17025 and ISO Guide 34 quality systems, as well as cGMPproduction capabilities. Over the past several decades CIL has increased itsglobal footprint and now has over 400 employees in its facilities located infour countries. The CIL group is comprised of five companies: CambridgeIsotope Laboratories, Inc. (CIL) and CIL Isotope Separations, LLC (CIS) in the US; CIL Canada in Montreal,Canada; Euriso-Top in Saclay, France;and ABX GmbH in Dresden, Germany.
CIL’s state-of-the-artproduction facilities are located at the company’s headquarters in Tewksbury, Massachusetts,and the company’s primary production laboratories are located in Andover, Massachusetts.Our isotope-separation facility located in Xenia, Ohio,houses the world’s largest 13C and 18Oisotope-separation facilities and the world’s only commercial D2O enrichmentcolumns.
產(chǎn)品分類:
1)定制合成化合物(CustomSynthesis):CIL一直為醫(yī)藥、農(nóng)業(yè)、政府和環(huán)境各界成功地完成多種化合物的合成。對客戶所要求的標(biāo)記化合物, CIL都會(huì)對其進(jìn)行研究和選擇更合適的標(biāo)記。
2)代謝底物(metabolic Substrates ):CIL提供最完全的代謝分析底物,包括用于研究蛋白質(zhì)和氨基酸代謝的氨基酸、葡萄糖代謝的碳水化合物和脂解作用的脂肪酸等。穩(wěn)定性同位素標(biāo)記物質(zhì)使研究者能以安全的方式對活體內(nèi)的代謝途徑進(jìn)行研究。
3)法醫(yī)檢驗(yàn)(Forensics ):對于復(fù)雜物質(zhì)中低含量分析物的量化檢測,最精確的方法是同位素稀釋和質(zhì)譜兩種技術(shù)結(jié)合。CIL為 法醫(yī)檢驗(yàn)提供量化的同位素標(biāo)記治療藥物標(biāo)準(zhǔn)。
4)NMR 溶劑 ( NMR Solvents ):應(yīng)用于結(jié)構(gòu)分析、定量分析和純度分析、化學(xué)途徑與反應(yīng)機(jī)、反應(yīng)動(dòng)力學(xué)等。
5)環(huán)境污染物標(biāo)準(zhǔn)液(Environmental Contaminant Standards ):CIL使一系列環(huán)境標(biāo)準(zhǔn)的概念得以發(fā)展,這些國際標(biāo)準(zhǔn)均由世界上先進(jìn)的超痕量分析實(shí)驗(yàn)室檢測和校正。二十多年來,CIL生產(chǎn)的二氧(雜)芑、二堊英、呋喃和PCBs、PAHs符合國際"Gold Standards"。檢測對象包括空氣、水、土壤、沉淀物和食品等。
6)13C的分離物 (13C Separation ):13C的年產(chǎn)量達(dá)120千克,使CIL成為世界上13C的最大生產(chǎn)商,也是診斷和研究應(yīng)用領(lǐng)域13C的重要供應(yīng)商。
7)18O的分離物 (18O Separation ):CIL生產(chǎn)的18O水, 既有符合PET技術(shù)要求的高豐度18O水(96%), 也有適合代謝研究實(shí)驗(yàn)的低豐度18O水(10%)。
8)同位素標(biāo)記金屬(Isotopicmetal):CIL提供大量種類齊全的穩(wěn)定同位素標(biāo)記金屬及金屬化合物。
CLM-173-PK ACETALDEHYDE (1,2-13C2, 99%)
DLM-112-PK ACETALDEHYDE (D4, 99%)
CLM-1161-PK ACETIC ANHYDRIDE (1,1',2,2'-13C4, 99%)
CLM-1159-PK ACETIC ANHYDRIDE (1,1'-13C2, 99%)
CDLM-9271-0 ACETIC ANHYDRIDE (13C4, 99%; D6, 98%)
CLM-1160-0.25 ACETIC ANHYDRIDE (2,2'-13C2, 99%)
CLM-1160-0.5 ACETIC ANHYDRIDE (2,2'-13C2, 99%)
CLM-1160-1 ACETIC ANHYDRIDE (2,2'-13C2, 99%)
DLM-1162-PK ACETIC ANHYDRIDE (D6, 98%)
DLM-9-PK ACETONE-D6 (D, 99.9%)
DLM-9TC-PK ACETONE-D6 (D, 99.9%) +0.03% V/V TMS
DLM-9TB-PK ACETONE-D6 (D, 99.9%) +0.05% V/V TMS
DLM-9TA-10 ACETONE-D6 (D, 99.9%) +1% V/V TMS
DLM-9TA-10X1 ACETONE-D6 (D, 99.9%) +1% V/V TMS
DLM-9TA-25 ACETONE-D6 (D, 99.9%) +1% V/V TMS
CLM-1260-0.5 ACETONITRILE (1-13C, 99%)
CLM-1260-1 ACETONITRILE (1-13C, 99%)
CLM-704-PK ACETYL CHLORIDE (1,2-13C2, 99%)
CDLM-6208-0.25 ACETYL CHLORIDE (13C2, 99%; D3, 98%)
DLM-247-PK ACETYL CHLORIDE (D3, 98%)
CLM-9270-0 ACRYLAMIDE (1-13C, 99%)
DLM-821-PK ACRYLAMIDE (2,3,3-D3, 98%)
OLM-7858-PK ADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT (GAMMA-18O4, 94%+)
CLM-8906-PK S-ADENOSYL-L-HOMOCYSTEINE (ADENOSINE-13C10, 98%)
CLM-714-PK ANILINE (13C6, 99%)
CLM-466-PK BARIUM CARBONATE (13C, 98%+)
DLM-2603-PK BENZENE (1,3,4,5-D4, 98%)
DLM-733-5 BENZENE (1,3,5-D3, 98%)
CLM-182-PK BENZENE (13C6, 99%)
CLM-1813-PK BENZOIC ACID (RING-13C6, 99%)
CLM-3010-0 BENZOYL CHLORIDE (CARBONYL-13C, 99%)
DLM-595-PK BENZOYL CHLORIDE (D5, 99%)
CNLM-3946-PK BETA-ALANINE (13C3, 98%+; 15N, 96-99%)
CLM-8756-PK BETA-ALANINE (13C3, 99%)
CLM-8755-PK BETA-ALANINE (3-13C, 99%)
CNLM-3440-PK BETA-ALANINE (3-13C, 99%; 15N, 98%)
CLM-1339-PK BROMOACETIC ACID (1,2-13C2, 99%)
CLM-871-PK BROMOBENZENE (13C6, 99%)
DLM-398-PK BROMOBENZENE (D5, 99%)
CLM-1829-0 CHLOROBENZENE (13C6, 99%)
CLM-3603-PK DIETHYL MALONATE (1,2,3-13C3, 99%)
CLM-521-0.25 DIETHYL MALONATE (1,3-13C2, 99%)
CLM-521-0.5 DIETHYL MALONATE (1,3-13C2, 99%)
CLM-521-1 DIETHYL MALONATE (1,3-13C2, 99%)
DLM-1174-10 DIETHYL MALONATE (2,2-D2, 98%)
CLM-495-PK DIETHYL MALONATE (2-13C, 99%)
CLM-266-PK DIMETHYL SULFATE (13C2, 99%)
DLM-196-10 DIMETHYL SULFATE (D6, 98%)
DLM-196-5 DIMETHYL SULFATE (D6, 98%)
DLM-267-PK DIMETHYLAMINE (D6, 99%)
NLM-8722-PK ETHANOLAMINE (15N, 98%)
DLM-552-PK ETHANOLAMINE (D4, 98%)
CLM-3297-PK ETHYL ACETOACETATE (1,2,3,4-13C4, 99%)
CLM-3297-MPT ETHYL ACETOACETATE (1,2,3,4-13C4, 99%) MICROBIOLOGICAL/PYROGEN TESTED
CLM-682-0.25 ETHYL ACETOACETATE (3,4-13C2, 99%)
CLM-682-0.5 ETHYL ACETOACETATE (3,4-13C2, 99%)
CLM-682-1 ETHYL ACETOACETATE (3,4-13C2, 99%)
CLM-681-0.5 ETHYL ACETOACETATE (3-13C, 99%)
CLM-681-1 ETHYL ACETOACETATE (3-13C, 99%)
CLM-1011-PK ETHYL BROMOACETATE (1,2-13C2, 99%)
CLM-1009-PK ETHYL BROMOACETATE (1-13C, 99%)
DLM-271-PK ETHYLENE OXIDE (D4, 98%) STABILIZED W/ 0.1% HYDROQUINONE
DLM-6711-PK N-ETHYLMALEIMIDE (ETHYL-D5, 98%)
CDLM-4599-PK FORMALDEHYDE (20% W/W IN D2O) (13C, 99%; D2, 98%)
CLM-806-PK FORMALDEHYDE (13C, 99%) (~20% W/W IN H2O)
DLM-805-PK FORMALDEHYDE (D2, 98%) (~20% W/W IN D2O)
DLM-1229-PK GLYCEROL (1,1,2,3,3-D5, 99%)
DLM-1229-MPT-PK GLYCEROL (1,1,2,3,3-D5, 99%) MICROBIOLOGICAL/PYROGEN TESTED
CNLM-7333-PK GUANIDINE:HBR (13C, 99%: 15N3, 98%)
CNLM-7138-0 GUANIDINE:HCL (13C, 99%; 15N3, 98%)
GTK-1000 INLIGHT? Glycan Tagging Kit
DLM-7249-PK IODOACETAMIDE (D4, 98%)
CLM-8824-PK IODOACETIC ACID (13C2, 99%)
CLM-3264-PK IODOACETIC ACID (2-13C, 99%)
DLM-272-PK IODOETHANE (D5, 99%) + COPPER WIRE
DLM-1136-5 ISOPROPANOL (DIMETHYL-D6, 98%)
DLM-1981-PK METHANESULFONIC ACID (D4, 97-98%)
CDLM-688-PK METHANOL (13C, 99%; D4, 99%)
DLM-598-PK METHANOL (D3, 99.5%)
CLM-360-PK METHYLAMINE:HCL (13C, 99%)
CDLM-8241-PK METHYLAMINE:HCL (13C, 99%; METHYL-D3, 98%)
CDNLM-8182-PK METHYLAMINE:HCL (13C, 99%; METHYL-D3, 98%; 15N, 98%)
NLM-361-PK METHYLAMINE:HCL (15N, 98%+)
DLM-289-PK METHYLAMINE:HCL (METHYL-D3, 98%)
CNLM-6088-0 O-METHYLISOUREA HYDROGEN CHLORIDE (ISOUREA-13C, 99%; 15N2, 98%) 95% PURE
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4 | 瑞禧2023更新 Azido-PEG8-acid疊氮八聚乙二醇羧酸 | 405 | 瑞禧生物 | 2023-01-03 |
5 | 嵌段共聚物4 arm-PEG-TK-NH2 /NHS/MAL | 461 | 瑞禧生物 | 2022-12-08 |
6 | 活性氧敏感聚合物TK-PPE 酮縮硫醇-聚磷酸酯 PPE-TK | 515 | 瑞禧生物 | 2022-12-08 |
7 | 功能化腙鍵響應(yīng)性磷脂 DSPE-Hyd-PEG-Alkyne/CHO/cRGD 醛基/多肽 | 522 | 瑞禧生物 | 2022-12-08 |