聚乙二醇(PEG)是一種用途較廣的聚醚高分子化合物,它可應用于眾多領域。PEG能夠溶解于水和許多溶劑中,且該聚合物具有優(yōu)異的生物相容性,在體內(nèi)能溶于組織液中,能被機體迅速排除體外而不產(chǎn)生任何副作用,更難得的是,當把PEG和其它分子偶合時,它的許多優(yōu)良性質(zhì)也會隨之轉(zhuǎn)移到結(jié)合物中。在藥物工業(yè)中聚乙二醇可用作藥物輔料以提高藥物的各種性能,如分散性、成膜性、潤滑性,緩釋性等。在新型生物材料的合成和改性中,聚乙二醇作為材料的一部分,將賦予材料新的特性和功能,如親水性、柔性等。

Under the protection of argon, the compound and oxolane were added to a 500ml round bottom flask, and the reaction liquid was cooled to about 0 ° C in an ice bath. Sodium hydride was added into the reaction system slowly in 3 batches for 30 min. The reaction mixture was heated to 40 a ° C and then 20 mL of HO-PEG4-Tos (4) Oxolane solution was slowly added to the reaction system with a syringe for 2 H. The reaction mixture was further stirred in argon atmosphere for 24h. After the reaction, 200ml brine was added to quench the excess sodium hydride, and the organic solvent was removed by vacuum evaporation. The crude slurry was extracted with dichloromethane (200ML × 3) , collected and combined with organic extract, washed with Sodium bicarbonate aqueous solution and 200mL water, and dried with anhydrous sodium sulfate, after collection and concentration, the crude oil was purified by silica gel column chromatography (V (dichloromethane) : V (methanol) = 95∶5) . The yield was 68.6% .

產(chǎn)品名稱： 紫杉醇-聚乙二醇-近紅外染料
英文名稱：PTX-PEG-IR825 
狀態(tài)：固體/粉末/溶液
產(chǎn)品規(guī)格：mg
保存：N/A
儲藏條件：N/A
儲存時間：1年
用途：科研
溫馨提醒：僅供科研，不能用于人體實驗


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溫馨提示:西安瑞禧生物供應產(chǎn)品僅用于科研,不能用于人體